Christmas Day and Boxing Day which fall on a Saturday and Sunday respectively, will be observed as official public holidays in the Cayman Islands on Monday, 27 and Tuesday 28 December 2021 respectively.

Official Public Holidays for 2021 are as follows:

- New Year’s Day: Friday, 1 January;
- National Heroes Day: Monday, 25 January;
- Ash Wednesday: Wednesday, 17 February;
- Good Friday: Friday, 2 April;
- Easter Monday: Monday, 5 April;
- Discovery Day: Monday, 17 May;
- Queen’s Birthday: Monday, 14 June (unconfirmed);
- Constitution Day: Monday, 5 July;
- Remembrance Day: Monday, 15 November;
- Christmas: Monday, 27 December (observed); and
- Boxing Day: Tuesday, 28 December (observed).